Le Retatrutide 5mg(research code LY3437943, also known as GLP-3) is a next-generation triagonist peptide developed by Eli Lilly. It simultaneously activates three key metabolic receptors:GLP-1(glucagon-like peptide-1),GIP(glucose-dependent insulinotropic polypeptide) and the receptor atglucagonThis triple synergistic action makes it one of the most studied peptides in research on obesity and metabolic disorders.
Mechanism of action
The simultaneous activation of GLP-1, GIP, and glucagon produces complementary effects: GLP-1 reduces appetite and slows gastric emptying; GIP improves insulin sensitivity and potentiates the action of GLP-1; glucagon increases energy expenditure and stimulates hepatic lipolysis. This metabolic convergence is reflected, in clinical studies, by abody weight reduction of up to 24% in 48 weeks(Phase 2 data, NEJM 2023).
5mg format — for whom?
The 5mg format is recommended for research protocols requiring very low doses or for an ultra-gradual introduction to Retatrutide. It allows for a minimalist approach, starting at 1mg per week, ideal for exploratory studies in small models. This format offers thebest entry pointto discover Retatrutide at the lowest cost.
Technical specifications
- HPLC Purity≥99%certified by Janoshik Analytical (accredited independent laboratory)
- Certificate of Analysis (COA) available per production batch
- Freeze-dried form — maximum stability at-20°Cfor 24 months
- Reconstitution with bacteriostatic water (0.9% benzyl alcohol)
- Molecular weight: 4,730.46 g/mol — Formula: C₂₁₀H₃₃₃N₅₁O₆₁
Storage and replenishment
Store the lyophilized vial at -20°C before reconstitution. After reconstitution with 0.5 to 1 mL of bacteriostatic water, the solution is stable for 4 weeks at +4°C. Avoid repeated freeze/thaw cycles. Handle under aseptic conditions for laboratory research.
Shipping and tracking
Each batch is traceable from freeze-drying to shipping. Discreet packaging within 48-72 hours to all of Europe (France, Belgium, Germany, Spain, Italy, Netherlands, Poland, Portugal). Secure SEPA bank transfer. This product is intended exclusively for scientific research.
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