Le MT2 10mg(Melanotan 2) is a synthetic cyclic analog of α-MSH (melanostimulating hormone), a non-selective agonist of melanocortin receptors. Its cyclic structure gives it greater stability and potency than the natural hormone, making MT2 one of the most studied peptides for research on melanogenesis, photoprotection, and appetite regulation.
Molecular mechanism of action
MT2 activates several melanocortin receptors: (1)MC1R agonism— stimulates melanocytes and the synthesis of melanin (eumelanin), inducing skin pigmentation; (2)MC4R agonism— modulates the central circuits of appetite and sexual function; (3)MC3R agonism— involved in energy homeostasis and inflammation; (4)photoprotection— Increased melanin strengthens the body's natural defenses against UV radiation; (5)structural stability— Cyclization prolongs the half-life compared to endogenous α-MSH.
Search applications
- Melanogenesis and skin pigmentation
- Photoprotection and response to UV
- Appetite regulation and energy homeostasis (MC4R pathway)
- Research on sexual function
- Study of melanocortin receptors
- Melanocortinic anti-inflammatory pathways
Analytical data
- Sequence :Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
- Molecular weight:1024.2 Da
- HPLC Purity:≥99% (Janoshik certified, COA available per batch)
- Shape :White, sterile lyophilized powder
- Solubility:Bacteriostatic water, sterile water, physiological saline solution
- Freeze-dried powder storage:Up to 24 months at -20°C
- Reconstituted storage:4 weeks at +4°C, away from light
Reconstitution & Storage
Reconstitute with sterile or bacteriostatic water (recommended concentration: 2–5 mg/mL). The reconstituted solution is stable for 4 weeks at +4°C, protected from light. The unreconstituted lyophilized powder can be stored for up to 24 months at -20°C. Avoid repeated freeze-thaw cycles and prolonged contact with air after reconstitution.
Shipping
Discreet shipping within 48-72 hours to all of Europe (France, Belgium, Germany, Spain, Italy, Netherlands, Poland, Portugal). Insulated packaging. Full traceability from freeze-drying to delivery. Payment via secure SEPA bank transfer. This product is intended exclusively for scientific research.
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