Le Semax 10mgSemax is a synthetic heptapeptide derived from the ACTH(4-10) fragment, developed in Russia as a nootropic and neuroprotective agent. Unlike ACTH, it lacks hormonal activity and specifically targets cognitive function and neuroprotection. Semax is among the most studied peptides for research on memory, attention, and neuronal recovery.
Molecular mechanism of action
Semax acts via several complementary neurochemical pathways: (1)modulation of the BDNF and the NGF— increases the expression of neurotrophic factors in the hippocampus, supporting synaptic plasticity; (2)dopaminergic and serotonergic regulation— influences neurotransmitter systems involved in attention and mood; (3)neuroprotection— reduces neuronal oxidative stress and protects against ischemia (stroke models); (4)enkephalinase inhibition— prolongs the action of endogenous regulatory peptides; (5)central anti-inflammatory action— modulates glial cytokines.
Search applications
- Cognition, working memory and learning
- Attention and concentration (ADHD models)
- Neuroprotection and post-ischemic (stroke) recovery
- Synaptic plasticity (BDNF/NGF pathways)
- Stress, anxiety, and neural resilience
- Research on mental clarity and cognitive performance
Analytical data
- Sequence :Met-Glu-His-Phe-Pro-Gly-Pro
- Molecular weight:813.9 Da
- HPLC Purity:≥99% (Janoshik certified, COA available per batch)
- Shape :White, sterile lyophilized powder
- Solubility:Bacteriostatic water, sterile water, physiological saline solution
- Freeze-dried powder storage:Up to 24 months at -20°C
- Reconstituted storage:4 weeks at +4°C, away from light
Reconstitution & Storage
Reconstitute with sterile or bacteriostatic water (recommended concentration: 2–5 mg/mL). The reconstituted solution is stable for 4 weeks at +4°C, protected from light. The unreconstituted lyophilized powder can be stored for up to 24 months at -20°C. Avoid repeated freeze-thaw cycles and prolonged contact with air after reconstitution.
Shipping
Discreet shipping within 48-72 hours to all of Europe (France, Belgium, Germany, Spain, Italy, Netherlands, Poland, Portugal). Insulated packaging. Full traceability from freeze-drying to delivery. Payment via secure SEPA bank transfer. This product is intended exclusively for scientific research.
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